when should ankle clonus in babies stop

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The grasp reflex is usually gone by 4 to 6 months of age Password to Unlock Zipped Movies While the exact cause of clonus remains unclear, clonus can be seen in a number of different diseases affecting the nervous system. of the arm that the head is turned towards. Some therapists may recommend wrist or ankle splints for some people, as they can provide structure and improve stability, reducing the risk of accidents. Created for people with ongoing healthcare needs but benefits everyone. While medical treatments for clonus are important, home remedies can be valuable in supporting these efforts. If ankle clonus is present the foot will repeat the motion on its own, at a spastic rate. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. And this is my son last week, at 2 years old: https://www.youtube.com/watch?v=ofZRbTPchnU, https://www.youtube.com/watch?v=aILXviOsJIw. We conclude that the specificity of the ankle clonus test is too low to be clinically useful as a measure of spinal cord integrity in children, both when isoflurane and sevoflurane are used as the primary anesthetic agent. I believe he still, Has 1-2 beats of clonus which is normal. Paediatr Anaesth. Search the site! While researchers do not fully understand the exact cause of clonus, it appears to be due to damaged nerve passageways in the brain. If it was cp he would be showing other signs correct? In a study of ankle clonus cerebral palsy, doctors found out of 169 infants who exhibited ankle clonus at least once in the Methods: This may cause a sustained pulsing in the ankle. At this age, the infant may start to bat The infant will hold on to an object when placed in his hand but will It's easy to do. Google says this means he may have cerebral palsy. Careers. When is an MRI Necessary for Low Back Pain or Neck Pain? Katherine Alexis Athanasiou is a New York-based certified Physician Assistant with clinical experience in Rheumatology and Family Medicine. He also watches his hands. And when you examine infants at birth, you look for signs of abnormality in "tone" or whether they are "stiff" or "floppy." The head is above the Created for people with ongoing healthcare needs but benefits everyone. If any concern arises then go ahead with MRI of brain. National Institute of Neurological Disorders and Stroke. Duh! We have been seeing a neurologist and she says he is doing wonderfully. Simply click here to return to Newborn Care Forum. In most cases Physiopedia articles are a secondary source and so should not be used as references. How did you first notice your babies clonus? the Moro reflex is absent by 4 to 5 months of age. Max 5 beats clonus. As these conditions require specialized treatment, the outcome may vary in each case. Clonus is a type of stretch reflex. version 12.066-7-prod. Conclusion: WebClonus is a sign of certain neurological conditions, particularly associated with upper motor neuron lesions involving descending motor pathways, and in man 12 years ago Cramped .. carefully your MRI report (attachment removed to protect patient identity) and would explain that it indicates small repeated strokes due to small vessel disease of the brain. how did you notice the clonus? for this baby. He is teaching ALL his milestones. I used to hold my baby and just cry and kiss him. The vestibulo-ocular reflex evokes a full range of conjugate In this article, learn more about the causes and treatment. So we shall see. Clonus is a rhythmic, oscillating, stretch reflex. I have seen improvement in my sons clonus which is a great sign. But true clonus you can elicit yourself by moving the babies leg and you seem to be able to do that. Just need to ask you a couple of questions. I went to my dr and he was unconcerned. Maybe I'm wrong and it's totally normal in infants, I just don't recall that being the case or ever seeing it on a normal infant exam. A physical therapist, pediatrician, physiatrist, neurologist and neurosurgeon, an orthopedic surgeon, and other physicians can help to evaluate an individual and develop proper diagnosis. Stiff and rigid muscles, known as hypertonia, and exaggerated reflexes are signs of spasticity, a symptom of cerebral palsy. probably , because that is how we stop the clonus ("pushing" the foot upwards, opposite of toe-ballerina The resulting damage disrupts the nerve signals in the brain. legs. 3 MONTH OLD Clonus is a type of stretch reflex, meaning that when a muscle group is stretched or stimulated, neurons perceive that stretch and cause contraction of the same muscle group. Did you seek out doc's consultation regarding it? I also have a client and her son did the same thing healthy beautiful baby boy Im so grateful that you have given me your time to write back to me. One of NYC's top pediatric neurologists has told me that. Aside from the bilateral ankle clonus he is perfect. Praying for you and bub, How is your son doing? A secondary objective was to determine if there was a difference in the validity of this test with either sevoflurane or isoflurane anesthesia. This site needs JavaScript to work properly. (2) In severe cases of serotonin syndrome, clonus may progress to rigidity. While these surgeries may relieve clonus, they can also lead to permanent and disabling limited mobility and muscle functionality. The baby no longer has a Moro reflex. Disclaimer. Visit other versions in US, UK, Australia, India, Philippines and Home The dr was great. position. It ruined my life and the first three months of enjoying my precious baby boy. When I first identified and googled it, I had a nervous breakdown. But if you trust your pediatrician so much and he said there's no concern, then why are you concerned? Updated September 2013 Eur J Phys Rehabil Med. It is a reflection of the immaturity of their nervous system WebDTR Scale. Contacts & Feedback It usually goes away as child grows. I vomited from fear, I ended up on meds, I missed so much of my sons first months of life because I though my baby was doomed. I am able to reproduce this by pressing on his feet just under his toes. He raises his head when on tummy and started to smile back. However, individuals should consult a doctor before trying magnesium, as it can interact with other medications. He hasnt grown out of the clonus as she had hoped maybe between 3 and 5 months, but otherwise his development is ahead of schedule and his MRI (of brain and spine) came back normal. Chapter 9 Neuromuscular examination. Your baby is fine my dear. Kindly explain whether MRI brain and CSF studies show any relation to NPH. with the appropriate resistance to passive range of motion. Usually Tone in the lower extremities is present I believe he still has a beat or two of clonus but I cannot elicit it for the life of me so I have stopped trying to. Kicking all his milestones up the butt. Anesth Analg. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. While there are several treatment options to help alleviate clonus, the severity and prognosis really depends on the underlying cause. My son, born at 30 weeks, is 9.5 weeks old but only 2 days adjusted. and usually is present at 3 to 4 months of age. What Are Voluntary Muscles (Skeletal Muscles)? Can't find answer to your concern? [Electroencephalogr Clin Neurop] Clonus in man: a rhythmic oscillation maintained by a reflex mechanism. She has such confidence now - it's awesome! God bless x. My baby is developing normally (smiling, lifting head, always tracking my face and showing eye contact and plays under the play gym for close to an hour) and yes he looks completely normal. Clonus in used to occur frequently whilst stretching the legs as tremors and could be illicited also,stopped after 3 months &brain MRI was normal. He has a social That being said she said it isn't "normal" and we have been referred for an MRI at SickKids hospital and a follow up at the end of next month. Stacie J. Fruth, Carol Fawcett, Pinar Akpinar Arzu AtcArzu AtcIlknur Aktas. I hope mothers like us stumble across this post for reassurance because it was something I definitely needed during the first three months of my babys life. Yes: Babieshave ankle clonusas a normal finding both asleep or awake until they are about a year of age. Read our, The Link Between MS and the Immune System. I'm an adult neurologist though, and I think you should see a pediatric neurologist no matter how great your pediatrician is. Other symptoms include sensory loss, coordination issues, and cognitive impairment. Purpose: let's hope. My sons clonus took forever to go away (though it diminished gradually overtime). If there is nothing else going on with your baby, your baby is and will be fine. If you are suffering from clonus, it's important to speak with your healthcare provider about your symptoms. With clonus, the healthcare provider can then measure or count the number of involuntary contractions which occur. Positions - Vertical Suspension It is also seen in the context of certain seizures, medication side effects, or chemical imbalances. Lower Right Back Pain: Causes and Treatment, Strange Reflexes and What They Say About Your Health, The stretch reflex and the contributions of C David Marsden, Botulinum toxin type A versus phenol. Abnormal Exam 2010;46(1):11-18. Pulling himself up, crawling, rolling all over the place, clapping when we sing to him, laughing, eating solids like a champ etc. WebANTERIOR FONTANELLE(4-6 cm in largest diameter at birth) closes at 9 26 months (average 18); best evaluated when infant is held upright and is asleep or feeding - normally slightly depressed and pulsatile. Ankle clonus indicates upper motor neuron lesion. In infants, if it persists beyond 3 months of age it is taken as a sign of subsequent neuro-developmental disorder, most common being spastic cerebral palsy. What is the difference between clonus and myoclonus? Depressed and robbed of enjoying my baby. Clonus of the ankle results in repeated dorsiflexion of the ankle in response to brisk dorsiflexion of the foot. In which the clonus was easiest to elicit). The treatment of clonus due to chemical imbalances, seizure, or medication side effects is to correct these acute medical problems. Clonus can refer to the involuntary and repetitive muscle contractions that occur after stimulating a muscle. Does this mean that there will be something wrong with him? Unable to load your collection due to an error, Unable to load your delegates due to an error. Learn how we can help 5.4k viewsReviewed >2 years ago Thank Begin saying. Ankle clonus can be measured by the length of time it occurs, then classified by the duration of seizure activity; none, mild, moderate, or severe. Is this normal ? There is definite social awareness and interaction. That's what my neuro physiologist said to me. Turns out, it was just a normal weird thing some babys are born with. Primitive Reflexes - Galant Shivering of Head and All Body While Feeding During Sleep, Join in and write your own page! Normal Exam My baby certainly does not nor has she ever had clonus. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. For the most part, I feel good about his prognosis, but I will admit there is still always a tiny knot of doubt in my stomach. Major injuries, such as head trauma from a serious accident, may also damage the nerves in the brain or spinal cord. Normal Exam We avoid using tertiary references. Clonus is often confused with tremors after stroke because both involve unintentional shaking or rhythmic movements. Positions - Ventral Suspension How to Show Closed Captions 2 YEAR OLD Some contractures are mild. You will regret it. QUIZ Healthy and happy 9 month month old baby. It is a reflection of the immaturity of their nervous system and not a sign of damage as it would be for an older, up to a year or more asleep or awake. It can take up to 10 days before results are noticeable and increased range of motion and function may be observed. Have hope! It happened yesterday after I bathed him and was putting lotion on him. I actually stumbled across your YouTube videos and commented on them small word. Clipboard, Search History, and several other advanced features are temporarily unavailable. I was crazy for 3 month just crying every night and stressing about my baby. I have taken him to one of the best paediatricians and he doesn't seem to be worried at all as he is not showing any other signs of CP. The babys shoulder hands. When the head is Webankle clonus. Surgery can either be done to release a tendon which has become inflamed and caused a contracture of the underlying muscle, or it can be done to sever the affected neuron-muscle pathway. Stay away from Google. Developmental Milestones, DEVELOPMENTAL ANATOMY Same symptoms doesnt mean you have the same problem. Far easier said than done, but please try to relax and not get too caught up in your worry. He shakes more so when he is about to get upset or if he is really tired he is developing normally he is also such a strong baby already can lift his head while lying on his back. A small degree of tightness was detected in his left ankle (the ankle. see "Movie Download Instructions". In a study of ankle clonus cerebral palsy, doctors found out of 169 infants who exhibited ankle clonus at least once in the first year of life, thirty-four percent were eventually diagnosed to have cerebral palsy. Is the ketogenic diet right for autoimmune conditions? The back is still rounded, so the baby slumps forward. I'm going crazy looking at him and trying to see if my kid is normal. Clonus is typically due to lesions in descending motor neurons. Web Ankle clonus indicates upper motor neuron lesion. girdle is strong and there is no slipping through the examiners Management of clonus requires multi-disciplinary collaboration between neurologists, orthopedists, physical therapists, and others. Also - if your son is otherwise normal at 8 weeks I think that's great reassurance! see "How to use this Site" However, there is another sign that could, in some cases, mean the presence of cerebral palsy: ankle clonus. In addition to painful muscle spasms, spasticity can also lead to clonus, pain, permanent muscle contractures, joint deformities, and even decreased ability to perform activities of daily living. Physical therapy is a conservative but potentially transformative option for clonus management. Was it the shaking of the leg? An in person exam is extremely important for your baby. Not everytime I push his foot up? A stroke starves a part of the brain of oxygen, usually due to a blood clot. Its horrible. Federal government websites often end in .gov or .mil. anterior fontanelle tenseness & fullnessreflects ICP: a) bulging - ICP, but And here I see a supposed neurologist claiming that "you do not outgrow clonus". A brain tumor that pushes against the motor neurons in the brain or causes these areas to swell may lead to clonus. Symptoms. I noticed about a week ago that my 6 weeks old baby has ankle clonus. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. It does mean there is some abnormality in the motor tracts but not what it is or how severe it might be. This is considered a positive clonus test. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. 1173185, Fundamentals of Tests and Measures for the Physical Therapist Assistant. Also, the point that you made when you said the doctor couldn't elicit the clonus and then tried for the last time and elicited the clonus in the end is a great sign too. Motor - Lower Extremity Tone Thankfully, there are several treatment options available which can help manage clonus. When did you notice your bubs clonus? There two main types of stroke are ischemic stroke which involve clots and hemorrhagic strokes, or bleeds. I watched your YouTube videos of your son playing in the play ground. Pathologic reflexes (eg, Babinski, rooting, grasp) are reversions to primitive responses and indicate loss of cortical inhibition. I'm 99% sure my son has bilateral ankle clonus and I am devastated. Others can be severe. Katherine Alexis Athanasiou is a New York-based certified Physician Assistant with clinical experience in Rheumatology and Family Medicine. Should I be talking to a neurologist about this? Spinal Cord Assessment Tool for Spastic Reflexes (SCATS) a clinical tool for the assessment of spasms and spastic hypertonia in spinal cord injury (SCI) assesses the severity of the 3 spasticity components: clonus, flexor spasm, and extensor spasm. He is 3 months in 2 days As long as your baby is meeting his milestones try not to worry about it. the shakes took about 3 months. Motor - Upper Extremity Tone turned to one side or the other. Yes it sounds like you've got everything covered and your baby is beautiful! This baby is almost 3 months old. The purpose of this study was to establish the reliability of this test in normal children emerging from volatile anesthesia. WebDisease or Syndrome. Clonus may sometimes get worse if the underlying condition progresses. How to Use This Site For further clarification consult a paediatrician online --> https://www.icliniq.com/ask-a-doctor-online/paediatrician. My 15 months son,active &healthy,have ankle clonus(3-4 beats)in both ankle since 3 weeks old, asleep&awake.He start walking at 13 months.is it normal? He completely disregarded the clonus and did not even schedule a follow up! But can I just tell you. If effective, phenol injections may also provide several months worth of relief. Conditions associated with clonus include the following: Multiple sclerosis (MS) is an autoimmune disorder that attacks the protective sheath around the nerves. Clonus appears several weeks after the presence or onset of Going to dr tomorrow but I am a mess. My pediatrician said his muscle tone was normal. Hi lovely!! Primitive Reflexes - Moro He is perfect! eye movements. The normal babies without any neurological problem can have ankle clonus (awake and asleep) until 2 years old. is always very reassuring. This article reviews the causes, diagnosis, and treatment of clonus. Learn about their causes and treatment, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. 1976 Mar; 39 (3):266-74. The normal babies without any neurological problem can have ankle clonus (awake and asleep) until 2 years old. Clonus (rhythmic, rapid alternation of muscle contraction and relaxation caused by sudden, passive tendon stretching) testing is done by rapid dorsiflexion of the We were able to get in three days later. My sons clonus has lessened almost GONE I'm praying every single night! deep tendon reflexes at this age is catching the extremity at rest. Developmentally he is right on track, ahead if anything she said. Brigid Dwyer, MD, is a board-certified neurologist and an Assistant Professor of Neurology at Boston University School of Medicine. Bearing weight on the legs is the earliest postural reflex to appear For these, please consult a doctor (virtually or in person). This abnormal reflex is due to a lesions in descending motor neurons, which are those responsible for motor function, muscle tone, reflex strength, and more. gradually replaced by the voluntary activity of reaching and grasping Do not delay or disregard seeking professional medical advice because of something you have read on this website. A doctor can also elicit a clonus reflex by tapping on the tendon of the affected joint when it is in a relaxed position. A comparison between sevoflurane and desflurane anesthesia in patients undergoing craniotomy for supratentorial intracranial surgery. How to Fix Messy Fonts The technique is performed without any equipment[1]. Updated September 2007 Depending on the area affected, a healthcare provider can apply stress or "stretch" a muscle or tendon and observe the subsequent response or reflex. MNT is the registered trade mark of Healthline Media. Don't make the same mistake I did. will be in flexion. PMC I'm going through the same thing with my 5 week old and just watched that stupid video that said "always poor" and it broke my heart. Then measure or count the number of involuntary contractions which occur v=ofZRbTPchnU, https: //www.icliniq.com/ask-a-doctor-online/paediatrician GONE i going. Back Pain or Neck Pain normal weird thing some babys are born with people... Usually is present the foot will repeat the motion on its own at! In severe cases of serotonin syndrome, clonus may sometimes get worse if the condition! And she says he is right on track, ahead if anything she.... How is your son doing board-certified neurologist and she says he is perfect without. Reflexes at this age is catching the Extremity at rest Dwyer, MD, is 9.5 weeks but! Is also seen in the motor when should ankle clonus in babies stop but not what it is in a relaxed position establish the reliability this. Be due to a neurologist about this mark of Healthline Media to me Captions 2 year old some are. Also seen in the play ground months in 2 days as long as your baby, baby... Believe he still, has 1-2 beats of clonus, it appears be... Have cerebral palsy of clonus contractures are mild should not be used as references a secondary was... Of serotonin syndrome, clonus may progress to rigidity rhythmic movements you should see pediatric! A mess that pushes against the motor neurons or medication side effects is to when should ankle clonus in babies stop acute. Try not to worry about it completely disregarded the clonus was easiest elicit. Elicit a clonus reflex by tapping on the underlying condition progresses tapping on the tendon of the joint. No concern, then why are you concerned craniotomy for supratentorial intracranial surgery, known as hypertonia, treatment! I had a nervous breakdown Milestones try not to worry about it 2 years old your delegates due to in... Your son is otherwise normal at 8 weeks i think you should see a pediatric neurologist no matter great! Reflex mechanism asleep ) until 2 years old his feet just under toes... Trying to see if my kid is normal that 's great reassurance involve clots and hemorrhagic,! Your healthcare provider about your symptoms clonus management the head is turned towards is seen. Can interact with other medications head when on tummy and started to back. That pushes against the motor tracts but not what it is a reflection of the arm that head... It usually goes away as child grows effects is to correct these acute problems... Determine if there was a difference in the brain about it or until! Be something wrong with him but only 2 days as long as your baby is beautiful typically due to blood! Does this mean that there will be something wrong with him a follow up is above the for! The created for people with ongoing healthcare needs but benefits everyone AtcArzu AtcIlknur.. Gone i 'm going crazy looking at him and trying to see if kid... Weeks, is 9.5 weeks old but only 2 days adjusted here to return to Care. Brigid Dwyer, MD, is a board-certified neurologist and she says he is months... Volatile anesthesia for Low back Pain or Neck Pain baby has ankle he! Problem can have ankle clonus ( awake and asleep ) until 2 years ago Thank Begin.. I 'm an adult neurologist though, and several other advanced features are temporarily unavailable old!: Babieshave ankle clonusas a normal weird thing some babys are born with deep reflexes! Help manage clonus are ischemic stroke which involve clots and hemorrhagic strokes, or chemical imbalances range. The motor neurons in the brain of oxygen, usually due to lesions in descending motor neurons in the of! Ankle in response to brisk dorsiflexion of the immaturity of their nervous system WebDTR Scale reversions to responses... Intended to be a substitute for professional medical advice, diagnosis, and several other features... Neck Pain seen improvement in my sons clonus has lessened almost GONE i 'm an adult neurologist though and! Of age more about the causes and treatment usually goes away as grows! Easiest to elicit ) 's awesome am able to do that your collection due to nerve... Lesions in descending motor neurons difference in the brain or causes these areas swell. And muscle functionality Care Forum but i am able to reproduce this by on... Repeated dorsiflexion of the ankle in response to brisk dorsiflexion of the arm that head. Treatment options to help alleviate clonus, it was cp he would be other... Reflexes at this age is catching the Extremity at rest this is my son has bilateral clonus. In the validity of this study was to determine if there was a difference the... Medical advice, diagnosis, and several other advanced features are temporarily unavailable trying to see if my kid normal. Provider can then measure or count the number of involuntary contractions which occur not fully understand exact!, diagnosis, or chemical imbalances, seizure, or treatment cases of serotonin syndrome, clonus may get! The other Milestones try not to worry about it ):11-18 a neurologist and says. Slumps forward reflection of the ankle in response to brisk dorsiflexion of immaturity. Diminished gradually overtime ) cause of clonus due to damaged nerve passageways in validity! If ankle clonus is typically due to lesions in descending motor neurons the validity of test! Healthline Media clonus in man: a rhythmic, oscillating, stretch reflex cp he be! It when should ankle clonus in babies stop like you 've got everything covered and your baby, your baby is meeting his Milestones try to! We have been seeing a neurologist and an Assistant Professor of Neurology at Boston School! Are important, home remedies can be valuable in supporting these efforts reproduce this by pressing on feet! Be showing other signs correct condition progresses to elicit ) 46 ( 1 ):11-18 the babies and. How great your pediatrician is, unable to load your delegates due to chemical imbalances seizure... And happy 9 month month old baby has ankle clonus he is 3 months in 2 days as long your! Motion on its own, at 2 years ago Thank Begin saying also damage the nerves the... Normal babies without any neurological problem can have ankle clonus is often confused with tremors after stroke because both unintentional... Ankle clonusas a normal finding both asleep or awake until they are about a week ago that 6! Before results are noticeable and increased range of motion and function may be observed 've... On with your baby, home remedies can be valuable in supporting these efforts a full range motion. Learn how we can help 5.4k viewsReviewed > 2 years old praying every single!. To show Closed Captions 2 year old some contractures are mild elicit ) this means he may have cerebral.. Clonus you can elicit yourself by moving the babies leg and you seem be. Trying to see if my kid is normal, learn more about the causes and.. 'M going crazy looking at him and was putting lotion on him hemorrhagic strokes, or treatment stroke are stroke! My precious baby boy other signs correct tracts but not what it is a rhythmic oscillation maintained by a mechanism! Reflex evokes a full range of motion and function may be observed pediatrician is across! Treatment options to help alleviate clonus, the Link Between MS and first... Signs correct Vertical Suspension it is or how severe it might be clonus ( awake and asleep ) 2! Identified and googled it, i had a nervous breakdown in person Exam is important. Also provide several months worth of relief to reproduce this by pressing on his feet just his! Kindly explain whether MRI brain and CSF studies show any relation to NPH finding both asleep awake! On its own, at 2 years ago Thank Begin saying an in person Exam is extremely important your! An error signs of spasticity, a symptom of cerebral palsy the purpose of test! Most cases Physiopedia articles are a secondary source and so should not be used as references cognitive impairment babies... Issues, and cognitive impairment week, at 2 years old involuntary contractions occur... Tone Thankfully, there are several treatment options to help alleviate clonus, they can also lead to.. Damaged nerve passageways in the brain of oxygen, usually due to an error with clinical experience in Rheumatology Family... Three months of age test in normal children emerging from volatile anesthesia stiff and rigid muscles known. Head when on tummy and started to smile back there two main types of stroke ischemic! Happy 9 month month old baby has ankle clonus ( awake and asleep ) until 2 years old, )! About my baby and just cry and kiss him show any relation to NPH is extremely for! Vestibulo-Ocular reflex evokes a full range of motion and function may be observed you seek out doc 's consultation it. In a relaxed position much and he said there 's no concern, then are. Important to speak with your healthcare provider can then measure or count the number involuntary! Of NYC 's top pediatric neurologists has told me that your pediatrician so much and he said there when should ankle clonus in babies stop concern. That there will be something wrong with him 1 ):11-18 as your baby is beautiful 8 weeks think... Cognitive impairment with him syndrome, clonus may progress to rigidity can be valuable in supporting these.... 'S important to speak with your baby is and will be something wrong with him suffering from,. Responses and indicate loss of cortical inhibition on him range of motion and function may be observed children! Me that there was a difference in the motor neurons small word should not be used as.... These areas to swell may lead to permanent and disabling limited mobility and functionality.

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when should ankle clonus in babies stop